the Association of Apnea Hypopnoea Index with Fall in Oxygen Saturation in Patients with Obstructive Sleep Apnea

Abstract

This study aimed to find out the association of Apnea Hypopnoea Index (AHI) with Fall in Oxygen Saturation in Patients with Obstructive Sleep Apnea (OSA). OSA Syndrome (OSAS) is quite common and results from a mechanical impediment that stops airflow during sleep. Such intervals lead to temporary oxygen deficiency, which can impact the body in numerous ways. This work explored the relationship between oxygen level and the Respiratory Event Index (REI) index to gain further insight into OSA. The results indicate that the Nadir Oxygen Saturation (SpO2) during sleep had a notable inverse correlation with REI (r = -0.72, p < 0.001). Positive correlation was also noted with Oxygen Desaturation Index's (ODIs) on REI (r=0.83 and p < 0.001). Regression analysis identified the ODI (Beta = 0.65, p < 0.001) and Nadir SpO2 during sleep (Beta = 0.13, p < 0.001) as significant predictors of desaturation. Conclusions: This research marks the clear relationships noted between REI and oxygen desaturation values, reinforcing concern over the ODI as an important predictor of OSA severity. Such results certainly change how OSA is approached in terms of its treatment or even advanced clinical management systems. The results clearly show the focus that needs to be done on capturing intermittent hypoxemia effects. New studies should be performed that are based on tracking subjects over prolonged periods to provide evidence and investigate the reasons why people differ in the way they respond to desaturation of oxygen.